Your life brings its share of surprises, smiles and frowns. All those experiences and facial expressions mean repeated muscle contractions, one of the factors that may lead to prominent lines. If you’re bothered by the lines on your forehead, around your eyes and between your brows, you’re not alone.
BOTOX® Cosmetic (anabotulinumtoxinA) is the first and only roduct of its kind that is FDA approved for moderate to severe lines in three areas.
$11 / Unit
FROWN LINES
FDA-APPROVED DOSING
Frown Lines — 20 UNITS
For temporary improvement of moderate to severe frown lines, BOTOX® Cosmetic is injected into the corrugator and procerus muscles in your brow area.
Results may vary. Photos taken at maximum frown before, 7 days after, and 30 days after treatment with BOTOX® Cosmetic. In clinical studies, physicians assessed 74% of adults had improvement at day 7, subjects assessed 82% had at least moderate improvement. At Day 30, physicians assessed 80% of adults had improvement, subjects assessed 89% had at least moderate improvement.2
CROW’S FEET
FDA-APPROVED DOSING
Crows Feet — 24 UNITS
For temporary improvement of moderate to severe crow’s feet lines, BOTOX® Cosmetic is injected into the orbicularis oculi muscle surrounding your eyes.
Results may vary. Photos taken at full smile before and 30 days after treatment with BOTOX® Cosmetic. Photos taken at full smile before and 7 days after treatment with BOTOX® Cosmetic. In 2 clinical studies, 26.1% and 20.3% of adults had a ≥ 2-grade improvement at day 30. In one of these studies, 67.9% had mild or no crow’s feet lines at day 30 after treatment.2
FOREHEAD LINES
FDA-APPROVED DOSING
Forehead Lines — 20 UNITS
For temporary improvement of moderate to severe forehead lines, BOTOX® Cosmetic is injected into the frontalis muscle above your eyebrows.
Results may vary. Photos taken at maximum eyebrow elevation before and 30 days after treatment with BOTOX® Cosmetic. Photos taken at maximum eyebrow elevation before and 7 days after treatment with BOTOX® Cosmetic. In 2 clinical studies of healthy adults, 61% and 46% had a ≥ 2-grade improvement in their forehead lines at day 30.2
1 Allergan Data on File, BOTOX Cosmetic 2015 WW Leader in Cosmetic NM Market, 2015.
2 BOTOX® Cosmetic Prescribing Information, 2017.
IMPORTANT SAFETY INFORMATION & APPROVED USES
BOTOX® Cosmetic may cause serious side effects that can be life threatening. Get medical help right away if you have any of these problems any time (hours to weeks) after injection of BOTOX® Cosmetic :
- Problems swallowing, speaking, or breathing, due to weakening of associated muscles, can be severe and result in loss of life. You are at the highest risk if these problems are pre-existing before injection. Swallowing problems may last for several months.
- Spread of toxin effects. The effect of botulinum toxin may affect areas away from the injection site and cause serious symptoms including: loss of strength and all-over muscle weakness, double vision, blurred vision and drooping eyelids, hoarseness or change or loss of voice, trouble saying words clearly, loss of bladder control, trouble breathing, and trouble swallowing.
BOTOX® Cosmetic dosing units are not the same as, or comparable to, any other botulinum toxin product .
There has not been a confirmed serious case of spread of toxin effect when BOTOX® Cosmetic has been used at the recommended dose to treat frown lines, crow’s feet lines, and/or forehead lines.
BOTOX® Cosmetic may cause loss of strength or general muscle weakness, vision problems, or dizziness within hours to weeks of taking BOTOX® Cosmetic. If this happens, do not drive a car, operate machinery, or do other dangerous activities.
Serious and/or immediate allergic reactions have been reported. They include: itching, rash, red itchy welts, wheezing, asthma symptoms, or dizziness or feeling faint. Get medical help right away if you are wheezing or have asthma symptoms, or if you become dizzy or faint.
Do not receive BOTOX® Cosmetic if you : are allergic to any of the ingredients in BOTOX® Cosmetic (see Medication Guide for ingredients); had an allergic reaction to any other botulinum toxin product such as Myobloc® (rimabotulinumtoxinB), Dysport® (abobotulinumtoxinA), or Xeomin® (incobotulinumtoxinA); have a skin infection at the planned injection site.
Tell your doctor about all your muscle or nerve conditions, such as ALS or Lou Gehrig’s disease, myasthenia gravis, or Lambert-Eaton syndrome, as you may be at increased risk of serious side effects including difficulty swallowing and difficulty breathing from typical doses of BOTOX® Cosmetic.
Tell your doctor about all your medical conditions, including: plans to have surgery; had surgery on your face; have trouble raising your eyebrows; drooping eyelids; any other abnormal facial change; are pregnant or plan to become pregnant (it is not known if BOTOX® Cosmetic can harm your unborn baby); are breast-feeding or plan to (it is not known if BOTOX® Cosmetic passes into breast milk).
Tell your doctor about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements. Using BOTOX® Cosmetic with certain other medicines may cause serious side effects. Do not start any new medicines until you have told your doctor that you have received BOTOX® Cosmetic in the past.
Tell your doctor if you have received any other botulinum toxin product in the last 4 months; have received injections of botulinum toxin such as Myobloc®, Dysport®, or Xeomin® in the past (tell your doctor exactly which product you received); have recently received an antibiotic by injection; take muscle relaxants; take an allergy or cold medicine; take a sleep medicine; take aspirin-like products or blood thinners.
Other side effects of BOTOX® Cosmetic include : dry mouth; discomfort or pain at the injection site; tiredness; headache; neck pain; and eye problems: double vision, blurred vision, decreased eyesight, drooping eyelids and eyebrows, swelling of your eyelids and dry eyes.
APPROVED USES
BOTOX® Cosmetic is a prescription medicine that is injected into muscles and used to temporarily improve the look of moderate to severe forehead lines, crow’s feet lines, and frown lines between the eyebrows in adults.
For more information refer to the Medication Guide or talk with your doctor.
To report a side effect, please call Allergan at 1-800-678-1605.
Please see BOTOX® Cosmetic full Product Information including Boxed Warning and Medication Guide.
